Ecological proteomics: Finding molecular markers that matter

Proteomics Analysis for Finding Serum Markers of Ovarian Cancer

A combination of peptide ligand library beads (PLLB) and 1D gel liquid chromatography-mass spectrometry/mass spectrometry (1DGel-LC-MS/MS) was employed to analyze serum samples from patients with ovarian cancer and from healthy controls. Proteomic analysis identified 1200 serum proteins, among which 57 proteins were upregulated and 10 were downregulated in the sera from cancer patients. Retinol...

Dark Chocolate and Metabolic Syndrome; Do Polyphenols All that Matter?

Molecular Markers in Neuroblastoma

Neuroblastoma, one of the common malignant childhood tumors, arises from neuroblast cells derived from theneural crest and destined for the adrenal medulla and the sympathetic nervous system and shows remarkable biologicalheterogeneity, resulting in favorable or unfavorable outcomes. Some tumors make rapid progress with a fataloutcome. In other instances, the tumors regress spontaneously in inf...

Ecological footprint of university students: Does gender matter?

To determine if there is a gender difference in the resource consumption activities of students in Central Mindanao University, a Philippine state university, an ecological foot printing study was conducted in August 2014. Consumption data from 380 student respondents were gathered using a survey questionnaire. A web-based software created by the Global Footprint Network was used to convert the...

Finding new sea legs for urine proteomics.

We draw attention to a commentary published in this issue of JASN by Knepper1 regarding studies undertaken in search of new biomarkers using urinary proteomics. Many of us who review or read these studies want important information to grace our journal pages. Proteomic technology today, even as it rapidly evolves, is capable of clever measurement and presentation, but harnessing this technology...